Trasplante autólogo de células madre hematopoyéticas para el síndrome antifosfolípido : presentación de un caso y revisión de la literatura.

El síndrome antifosfolípido refractario representa un desafío para prevenir la trombosis que puede ocurrir a pesar de la terapia adecuada de anticoagulación e inmunomodulación. Aquí, presentamos un paciente masculino de 35 años que presentó eventos tromboembólicos venosos variables. Se realizó trasplante de células madre hematopoyéticas autólogas después del acondicionamiento con ciclofosfamida y globulina antitimocítica. Cinco años después del trasplante, el tratamiento continuó mostrando un resultado exitoso en la prevención de nuevos eventos trombóticos. El trasplante autólogo de células madre hematopoyéticas representa una posibilidad de curación del síndrome antifosfolípido a pesar de la escasez de datos informados hasta el momento.

 

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